Evaluating the effectiveness, patient satisfaction, and cosmetic effects of a multipurpose healing cream powered by microbiome effect in individuals with inflammatory skin conditions

Nazmy, Nader Nasr; Kamel, Marwa; Attia, Abeer; Youssef, Eman Kamal; ElSaady, Dina; Shehtaha, Hany; Elhawary, Esraa Elsayed; El Tewsiy, Howaida; Ahmed El-Samongy, Marwa; Abdelshakour, Mohamed; ElMakhzangy, Rony; Ragheb, Asmaa; Ramez, Shahenda Ahmed; Khairy, Aml; El Mostafa, Shady; Nouman, Reem; Abd ElRahman, Mariam

doi:10.21608/ijhegy.2025.347243.1053

Evaluating the effectiveness, patient satisfaction, and cosmetic effects of a multipurpose healing cream powered by microbiome effect in individuals with inflammatory skin conditions

Document Type : Original Article

Authors

¹ Department of Dermatology and Laser, Faculty of Medicine, Benha University, Egypt

² Department of Dermatology and Laser, Faculty of Medicine, Cairo University, Egypt

³ Department of Dermatology and Laser, Faculty of Medicine, Assuit University, Egypt

⁴ Department of Dermatology and Venereology, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt.

⁵ Department of Dermatology, Faculty of Medicine, Tanta University, Egypt

⁶ Department of Dermatology, Faculty of Medicine, Al-Azhar University, Egypt

⁷ Department of Family Health, Faculty of Medicine, Alexandria University, Egypt

⁸ Department of Dermatology and Venereology, Medical Research and Clinical Studies Institute, National Research Centre, Cairo, Egypt

⁹ Department of Dermatology and Aesthetic Medicine, Faculty of Medicine, Mansoura University, Egypt

¹⁰ Department of Dermatology and Aesthetic Medicine, Faculty of Medicine, Ain Shams University, Egypt

10.21608/ijhegy.2025.347243.1053

Abstract

Background: The skin microbiome protects against pathogens and supports immunity. Dysbiosis can cause skin conditions; La Roche-Posay Thermal Spring Water, rich in prebiotics, help restore balance and reduce inflammation. This study evaluated the effectiveness, patient satisfaction, and cosmetic effects of a multipurpose healing cream with microbiome effect in inflammatory skin conditions. Methods: We conducted an observational survey of 212 Egyptian patients using dermocosmetic (DC) multipurpose healing cream as part of their standard care Assessments occurred at initial and follow-up visits from 2-4 weeks. Data on clinical signs, symptoms, effectiveness, cosmetic features, and satisfaction were collected via expert-validated surveys. Statistical analysis was conducted using SPSS version 27. We performed descriptive and comparative analyses using different tests depending on the variable characteristics. Results: Participants (median age 28; 84.9% female) primarily had skin phototypes II to VI, with phototype III being most common (48.6%). Lesions were mostly 3-10 cm (46.2%) or larger than 10 cm (40.6%), primarily on the face (55.7%). Significant improvement was noted in erythema, desquamation, pigmentation, cracks, and edema (P-value = 0.0001). Symptoms like tightness, pain, burning, and tingling significantly improved. Additionally, 97.6% of patients reported satisfaction with the cream’s soothing effects, and it was favorably rated for texture, application ease, and suitability across skin types. Conclusions: The DC multipurpose healing cream significantly improves clinical presentation, and cosmetic satisfaction in individuals with various skin conditions. Further research is recommended to validate these results and explore the effectiveness in combination with other treatments.

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